ROCESSES OF OBTAINING HYBRID ALGINATE-CHITOSAN AEROGELS AND STUDY OF THEIR ANTIBACTERIAL ACTIVITY
Abstract
Hybrid aerogels based on biopolymers are promising materials for biomedical applica-tions due to their unique controlled porous structure and biocompatibility. Biopolymers such as algi-nate and chitosan have become widespread; however, their individual aerogels often have limited sta-bility and low antibacterial activity. In this paper, a new method for obtaining hybrid alginate-chitosan aerogels aimed at overcoming these limitations has been developed. The proposed approach allows ob-taining materials with a high specific surface area (up to 273 m2/g) and mesopore volume (up to 1.37 cm3/g) and antibacterial activity against Staphylococcus epidermidis and Escherichia coli. The devel-oped hybrid aerogels can be used as medical devices (wound dressings, implants) and drug delivery systems. The study contributes to the development of environmentally friendly materials relevant for solving problems in medicine and pharmaceuticals, and provides a basis for further optimization of the functional properties of hybrid aerogels based on biopolymers.
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